HitPredict

Interactor 1: NMDE3 (Q01098)
Glutamate receptor ionotropic, NMDA 2C (GluN2C) (Glutamate [NMDA] receptor subunit epsilon-3) (N-methyl D-aspartate receptor subtype 2C) (NMDAR2C) (NR2C)
Gene: Grin2c

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 0.60 0.576

The method score is based on:

Property Details
Experiments 9647694, 19455133
Identification Methods two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0030165 - PDZ domain binding
GO:0045211 - postsynaptic membrane
GO:0048168 - regulation of neuronal synaptic plasticity
GO:0050885 - neuromuscular process controlling balance
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1239
Mm

1 724
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Last updated: 15 Jul 2024