HitPredict

Interactor 1: CDC42 (Q01112)
Cell division control protein 42 homolog (CDC42Sp)
Gene: CDC42

Interactor 2: GEF1 (Q09763)
Rho guanine nucleotide exchange factor gef1
Gene: GEF1

Species: Schizosaccharomyces pombe 972h-

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 12529446, 12972551, 17363901
Identification Methods affinity chromatography technology, enzymatic study, two hybrid, pull down, anti tag coimmunoprecipitation, molecular sieving
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~RhoGEF
Common GO terms GO:0032153 - cell division site
GO:0032955 - regulation of division septum assembly
GO:0051285 - cell cortex of cell tip
GO:0051286 - cell tip
GO:0110085 - mitotic actomyosin contractile ring
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 192
Sp

1 753
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Last updated: 15 Jul 2024