HitPredict

Interactor 1: CDC42 (Q01112)
Cell division control protein 42 homolog (CDC42Sp)
Gene: CDC42

Interactor 2: HOB3 (Q9UUM7)
Protein hob3 (Homolog of Bin3)
Gene: HOB3

Species: Schizosaccharomyces pombe 972h-

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.534

Property	Details
Experiments	17363901
Identification Methods	affinity chromatography technology, pull down, molecular sieving
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis GO:0007015 - actin filament organization GO:0043332 - mating projection tip GO:0051285 - cell cortex of cell tip
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 192 Sp			1 264
+	Hs
		925374 RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23		DNMBP_HUMAN (1-253): 7.61e-66: 223: 20.16
+	Hs
		131231 RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23		BIN1_HUMAN (5-240): 5.27e-68: 222: 19.48
+	Hs
		951095 RHOG_HUMAN (1-192): 1.47e-77: 231: 58.33		DNMBP_HUMAN (1-253): 7.61e-66: 223: 20.16
+	Hs
		894149 CDC42_HUMAN (1-192): 5.71e-77: 230: 81.25		DNMBP_HUMAN (1-253): 7.61e-66: 223: 20.16
+	Hs
		892443 RAC3_HUMAN (1-191): 1.99e-76: 228: 67.54		DNMBP_HUMAN (1-253): 7.61e-66: 223: 20.16
+	Hs
		925354 RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23		RHG17_HUMAN (6-251): 3.48e-59: 203: 15.97
+	Hs
		894126 CDC42_HUMAN (1-192): 5.71e-77: 230: 81.25		RHG17_HUMAN (6-251): 3.48e-59: 203: 15.97
+	Hs
		925314 RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23		RHG44_HUMAN (6-249): 2.1e-52: 183: 15.27
+	Hs
		894068 CDC42_HUMAN (1-192): 5.71e-77: 230: 81.25		RHG44_HUMAN (6-249): 2.1e-52: 183: 15.27
+	Hs
		925755 RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23		3BP1_HUMAN (6-237): 4.12e-35: 134: 12.98
+	Hs
		894476 CDC42_HUMAN (1-192): 5.71e-77: 230: 81.25		BIN3_HUMAN (20-259): 1.25e-41: 144: 27.05