HitPredict

Interactor 1: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing and 2 others more... GO:0008380 - RNA splicing GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 221 Hs			1 238
+	Hs
		1073601 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		RB15B_HUMAN (4-232): 1.77e-31: 123: 22.41
+	Hs
		1073605 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		PPIL4_HUMAN (1-84): 1.75e-25: 105: 26.97
+	Hs
		951977 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		516425 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Zm
		30171 A0A1D6K4S7_MAIZE (3-93): 2.97e-41: 146: 47.83		A0A1D6M1U3_MAIZE (11-132): 2.52e-25: 103: 32.03
+	Hs
		432527 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		1073633 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		RBM4_HUMAN (12-89): 4.44e-14: 72.2: 33.33
+	Hs
		516466 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		951927 SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		516495 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		516478 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		516339 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		963969 SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		432678 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		516689 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		PABP3_HUMAN (6-192): 4.81e-18: 84.4: 14.74
+	Hs
		951937 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		516471 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		TIAR_HUMAN (5-97): 6.64e-16: 77.8: 25.51
+	Hs
		516484 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		516674 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		RBM4_HUMAN (12-89): 4.44e-14: 72.2: 33.33
+	Hs
		474019 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		PAB4L_HUMAN (12-95): 5.81e-17: 80.5: 26.97