HitPredict

Interactor 1: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Interactor 2: MET14 (Q9HCE5)
N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14) (hMETTL14)
Gene: METTL14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29507755, 36597993
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 221 Hs			1 456
+	Hs
		1073642 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		1310284 SRSF8_HUMAN (1-183): 4.13e-29: 111: 63.39		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		1336049 PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76		MET14_HUMAN (1-433): 0: 654: 100.00
+	Hs
		964017 SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00		MTA70_HUMAN (161-391): 2.46e-88: 282: 29.00
+	Hs
		1199111 PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76		MTA70_HUMAN (161-391): 2.46e-88: 282: 29.00