Interactor 1: RUNX1 (Q01196)
Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit)
Gene: RUNX1

Interactor 2: HIPK2 (Q9H2X6)
Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)
Gene: HIPK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.620

The method score is based on:

Property Details
Experiments 16917507
Identification Methods affinity chromatography technology, enzymatic study, protein kinase assay, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030182 - neuron differentiation
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 453
Hs

1 1198
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024