Interactor 1: RELB (Q01201)
Transcription factor RelB (I-Rel)
Gene: RELB

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.980

The method score is based on:

Property Details
Experiments 29084252, 27609421, 35271311, 36629882, 21884980, 28514442, 14743216, 33961781, 16951372, 12657634, 15722553, 19122653, 22808155
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, electrophoretic mobility supershift assay, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RHD_dimer~RHD_dimer, RHD_DNA_bind~RHD_dimer, RHD_DNA_bind~RHD_DNA_bind
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 10 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 579
Hs

1 551
+ Hs
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+ Mm
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+ Gg
+ Hs
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+ Hs

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Last updated: 15 Jul 2024