Interactor 1: EGFR (Q01279)
Epidermal growth factor receptor (EC 2.7.10.1)
Gene: EGFR

Interactor 2: SOS1 (Q62245)
Son of sevenless homolog 1 (SOS-1) (mSOS-1)
Gene: SOS1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 8479540, 23027125, 18174162
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr
Common GO terms GO:0001942 - hair follicle development
GO:0005886 - plasma membrane
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0042127 - regulation of cell population proliferation
GO:0061029 - eyelid development in camera-type eye
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1210
Mm

1 1319
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024