HitPredict

Interactor 1: NOP3 (Q01560)
Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 (Mitochondrial targeting suppressor 1 protein) (Nuclear polyadenylated RNA-binding protein 1) (Nuclear protein localization protein 3) (Polyadenylate-binding protein NPL3)
Gene: NPL3

Interactor 2: MTR10 (Q99189)
mRNA transport regulator MTR10
Gene: MTR10

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.893

Property	Details
Experiments	10952997, 9412460, 9545233, 25838545
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~Xpo1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 414 Sc			1 972
+	Hs
		162698 SRSF6_HUMAN (126-274): 1.55e-44: 159: 25.82		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Hs
		162664 SRSF1_HUMAN (117-264): 1.06e-42: 152: 26.40		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Hs
		1028635 SRSF9_HUMAN (118-264): 2.33e-47: 163: 27.81		TNPO3_HUMAN (5-963): 9.67e-151: 471: 21.39
+	Hs
		162697 SRSF5_HUMAN (122-272): 1.04e-33: 128: 25.00		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Hs
		993013 SRSF1_HUMAN (117-264): 1.06e-42: 152: 26.40		TNPO3_HUMAN (5-963): 9.67e-151: 471: 21.39
+	Dm
		1359288 Q9V3W7_DROME (120-273): 1.44e-40: 146: 28.13		Q9VQG0_DROME (1-963): 1.33e-149: 469: 21.17
+	Dm
		644445 SRR55_DROME (125-273): 7.46e-33: 128: 25.26		Q9VQG0_DROME (1-963): 1.33e-149: 469: 21.17
+	Hs
		162812 PAP1L_HUMAN (94-212): 7.69e-17: 84.5: 20.80		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	At
		186863 SR34_ARATH (123-264): 4.6e-30: 119: 26.82		MOS14_ARATH (6-964): 1.58e-147: 464: 18.14
+	Xl
		1144988 Q640I0_XENLA (115-200): 9.01e-17: 82.9: 23.26		Q6NS03_XENLA (2-959): 4.72e-158: 495: 12.50
+	Hs
		162702 PABP4_HUMAN (190-285): 2.3e-13: 73.7: 15.15		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Hs
		162372 PABP1_HUMAN (190-285): 3.21e-12: 70.3: 15.15		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Hs
		162636 TIAR_HUMAN (192-287): 2.59e-09: 60.7: 13.40		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Hs
		163222 RBM4_HUMAN (199-278): 2.55e-09: 60.7: 16.25		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Sc
		633922 GBP2_YEAST (124-272): 1.18e-16: 83.1: 25.86		XPO1_YEAST (2-969): 6.84e-139: 445: 13.57
+	Sc
		376677 PABP_YEAST (202-285): 1.62e-11: 68: 18.39		XPO1_YEAST (2-969): 6.84e-139: 445: 13.57
+	Ce
		248174 Q20084_CAEEL (127-197): 2.62e-13: 73.2: 29.49		O62332_CAEEL (5-870): 2.43e-106: 353: 11.01
+	Dm
		1097895 Q24474_DROME (197-276): 3.31e-12: 69.8: 18.07		Q8MSM3_DROME (78-864): 2.33e-103: 344: 11.68