HitPredict

Interactor 1: SED5 (Q01590)
Integral membrane protein SED5
Gene: SED5

Interactor 2: NYV1 (Q12255)
Vacuolar v-SNARE NYV1 (R-SNARE NYV1) (New v-SNARE 1) (Synaptobrevin NYV1)
Gene: NYV1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	11994317, 24589832
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0006886 - intracellular protein transport GO:0006906 - vesicle fusion GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Sc			1 253
+	At
		1352876 SYP43_ARATH (1-339): 6.7e-57: 189: 11.99		VA721_ARATH (50-232): 1.69e-56: 181: 19.67
+	At
		249598 SYP41_ARATH (1-339): 2.68e-54: 182: 11.11		VA721_ARATH (50-232): 1.69e-56: 181: 19.67
+	Sc
		605868 SED5_YEAST (1-340): 6.94e-64: 207: 100.00		SEC22_YEAST (35-253): 2.75e-45: 153: 16.82
+	Dm
		1097995 STX5_DROME (1-325): 2.73e-60: 201: 30.77		Q7JYX5_DROME (49-247): 1.78e-43: 148: 19.05
+	Rn
		996534 STX5_RAT (1-324): 1.6e-57: 191: 29.32		SC22B_RAT (47-253): 2.16e-43: 148: 14.49
+	Dm
		115804 STX5_DROME (1-325): 2.73e-60: 201: 30.77		M9PGI6_DROME (35-248): 4.75e-38: 134: 12.79
+	Mm
		139056 STX1A_MOUSE (85-337): 3.85e-54: 180: 13.28		SC22B_MOUSE (47-253): 2.16e-43: 148: 14.49
+	Mm
		936372 Q8BH40_MOUSE (95-339): 3.77e-54: 180: 18.70		VAMP7_MOUSE (49-232): 4e-43: 147: 21.54
+	Dm
		577219 STX5_DROME (1-325): 2.73e-60: 201: 30.77		SYB_DROME (146-248): 2.48e-31: 114: 20.39
+	Dm
		1098015 STX5_DROME (1-325): 2.73e-60: 201: 30.77		Q9W3M8_DROME (92-221): 1.52e-27: 106: 17.78
+	Sc
		704534 SED5_YEAST (1-340): 6.94e-64: 207: 100.00		SNC2_YEAST (153-231): 8.71e-25: 96.8: 32.91
+	Mm
		1225102 STX5_MOUSE (1-324): 4.22e-57: 190: 29.63		YKT6_MOUSE (92-221): 2.5e-30: 113: 20.00
+	Rn
		996535 STX5_RAT (1-324): 1.6e-57: 191: 29.32		YKT6_RAT (92-221): 4.44e-30: 112: 19.26
+	Mm
		926191 Q8BH40_MOUSE (95-339): 3.77e-54: 180: 18.70		VAMP3_MOUSE (153-233): 3.01e-30: 110: 28.40
+	Mm
		192845 STX1A_MOUSE (85-337): 3.85e-54: 180: 13.28		VAMP2_MOUSE (163-250): 2.34e-29: 108: 27.27
+	Rn
		699175 STX1A_RAT (85-337): 5.79e-54: 180: 13.28		VAMP2_RAT (163-250): 2.34e-29: 108: 27.27
+	Mm
		926344 Q8BH40_MOUSE (95-339): 3.77e-54: 180: 18.70		VAMP2_MOUSE (163-250): 2.34e-29: 108: 27.27
+	Rn
		699182 STX1A_RAT (85-337): 5.79e-54: 180: 13.28		VAMP1_RAT (161-251): 4.34e-28: 105: 26.37
+	At
		249597 SYP41_ARATH (1-339): 2.68e-54: 182: 11.11		YKT61_ARATH (126-221): 1.11e-22: 93.7: 21.78
+	Mm
		250785 Q8BH40_MOUSE (95-339): 3.77e-54: 180: 18.70		VAMP8_MOUSE (165-231): 2.35e-24: 95.2: 26.87