HitPredict

Interactor 1: HNRPK (P61978)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (Transformation up-regulated nuclear protein) (TUNP)
Gene: HNRNPK

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0048024 - regulation of mRNA splicing, via spliceosome GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Hs			1 582
+	Mm
		965995 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		LARP7_MOUSE (8-582): 2.67e-121: 371: 79.20
+	Hs
		1194497 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00
+	Hs
		1194423 IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71		LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00
+	Mm
		732102 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		LA_MOUSE (24-227): 1.67e-45: 167: 25.00
+	Hs
		550205 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29
+	Mm
		710981 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		PABP1_MOUSE (1-389): 1.46e-40: 158: 10.45
+	Hs
		965694 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		ELAV1_HUMAN (92-211): 7.75e-13: 71.9: 22.50
+	Mm
		965986 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		ELAV1_MOUSE (92-211): 6.46e-13: 71.9: 22.50
+	Hs
		1102147 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98
+	Hs
		550547 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29
+	Hs
		1259184 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		LARP4_HUMAN (22-216): 3.24e-40: 157: 21.32
+	Hs
		1365715 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		LAR4B_HUMAN (2-216): 8.51e-36: 145: 17.02
+	Hs
		431263 IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71		LA_HUMAN (24-365): 5.99e-44: 163: 18.83
+	Hs
		1102118 IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71		PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98
+	Hs
		1387920 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		PABP5_HUMAN (12-206): 3.66e-32: 129: 14.15
+	Hs
		550500 IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71		PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29
+	Hs
		1259167 IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71		LARP4_HUMAN (22-216): 3.24e-40: 157: 21.32
+	Hs
		1245782 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		LARP1_HUMAN (29-114): 6.38e-13: 73.8: 40.23
+	Hs
		1152690 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		ELAV1_HUMAN (92-211): 7.75e-13: 71.9: 22.50
+	Hs
		1152660 IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71		ELAV1_HUMAN (92-211): 7.75e-13: 71.9: 22.50