HitPredict

Interactor 1: IFM3 (Q01628)
Interferon-induced transmembrane protein 3 (Dispanin subfamily A member 2b) (DSPA2b) (Interferon-inducible protein 1-8U)
Gene: IFITM3

Interactor 2: RTN4 (Q9NQC3)
Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5)
Gene: RTN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	33961781, 30833792, 34709727
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 133 Hs			1 1192
+	Hs
		92802 E9PS44_HUMAN (22-133): 6.07e-65: 194: 100.00		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		526071 IFM1_HUMAN (22-127): 6.41e-59: 179: 83.02		RTN4_HUMAN (1-1192): 3.85e-113: 383: 100.00
+	Hs
		307023 IFM3_HUMAN (1-133): 9.31e-80: 232: 100.00		RTN3_HUMAN (269-1191): 7.4e-55: 210: 22.06
+	Hs
		965692 IFM3_HUMAN (1-133): 9.31e-80: 232: 100.00		RTN1_HUMAN (419-1192): 1e-50: 194: 23.36
+	Hs
		258921 IFM3_HUMAN (1-133): 9.31e-80: 232: 100.00		RTN2_HUMAN (775-1185): 4.86e-44: 171: 25.39