HitPredict

Interactor 1: TFAP4 (Q01664)
Transcription factor AP-4 (Activating enhancer-binding protein 4) (Class C basic helix-loop-helix protein 41) (bHLHc41)
Gene: TFAP4

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

Property	Details
Experiments	28514442, 33961781, 24500709, 25332235, 25900982, 25515538, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 338 Hs			1 542
+	Hs
		966309 TFAP4_HUMAN (1-338): 5.12e-162: 457: 100.00		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59