HitPredict

Interactor 1: ACTHR (Q01718)
Adrenocorticotropic hormone receptor (ACTH receptor) (ACTH-R) (Adrenocorticotropin receptor) (Melanocortin receptor 2) (MC2-R)
Gene: MC2R

Interactor 2: MRAP (Q8TCY5)
Melanocortin-2 receptor accessory protein (B27) (Fat cell-specific low molecular weight protein) (Fat tissue-specific low MW protein)
Gene: MRAP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.710

Property	Details
Experiments	28298427, 21862608, 18077336, 19151134, 18840636
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 172
+	Hs
		785334 MC3R_HUMAN (16-292): 1.46e-86: 263: 46.50		MRAP_HUMAN (1-172): 1.25e-115: 326: 100.00
+	Hs
		966352 MSHR_HUMAN (21-294): 4.59e-78: 241: 40.78		MRAP_HUMAN (1-172): 1.25e-115: 326: 100.00
+	Hs
		702466 MC5R_HUMAN (5-293): 6.89e-58: 190: 45.15		MRAP_HUMAN (1-172): 1.25e-115: 326: 100.00
+	Hs
		686595 MC4R_HUMAN (6-293): 4.69e-57: 188: 46.44		MRAP_HUMAN (1-172): 1.25e-115: 326: 100.00
+	Hs
		785335 MC3R_HUMAN (16-292): 1.46e-86: 263: 46.50		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54
+	Hs
		966353 MSHR_HUMAN (21-294): 4.59e-78: 241: 40.78		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54
+	Hs
		966342 ACTHR_HUMAN (1-297): 9.39e-60: 194: 100.00		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54
+	Hs
		702467 MC5R_HUMAN (5-293): 6.89e-58: 190: 45.15		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54
+	Hs
		686596 MC4R_HUMAN (6-293): 4.69e-57: 188: 46.44		MRAP2_HUMAN (1-71): 6.49e-35: 122: 40.54