HitPredict

Interactor 1: AT2B2 (Q01814)
Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)
Gene: ATP2B2

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1243 Hs			1 618
+	Hs
		545205 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		588571 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		588572 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		588605 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		588588 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		588583 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		619234 AT2B4_HUMAN (1-1243): 0: 1154: 68.56		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		588580 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		588581 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		588576 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		588675 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		436156 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120302 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		564410 AT2B1_HUMAN (1-1243): 0: 1186: 78.86		RHOQ_HUMAN (5-169): 2.02e-10: 62.8: 26.26
+	Hs
		619221 AT2B4_HUMAN (1-1243): 0: 1154: 68.56		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		561551 AT2A2_HUMAN (53-310): 1.78e-54: 209: 27.68		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		561542 AT2A2_HUMAN (53-310): 1.78e-54: 209: 27.68		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		561689 AT2A2_HUMAN (53-310): 1.78e-54: 209: 27.68		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67