HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 656 Hs			1 2115
+	Hs
		1061192 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		726823 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		1068620 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		967188 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		318620 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		967176 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		GOGB1_HUMAN (1105-2077): 1.12e-19: 99.3: 9.49
+	Hs
		725096 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Hs
		726832 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37