HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	24999758, 30962207
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 656 Hs			1 1214
+	Hs
		1251591 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		1271152 RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		967321 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		726946 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Mm
		956888 EYA1_MOUSE (3-277): 2.57e-40: 157: 22.50		SMRC2_MOUSE (1-1203): 0: 957: 96.51
+	Hs
		726971 FUS_HUMAN (55-545): 1.15e-31: 131: 30.35		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		261473 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		318762 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		118513 EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16		HGS_HUMAN (668-1181): 1.12e-46: 182: 19.20
+	Hs
		867093 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		SC24C_HUMAN (1005-1213): 5.27e-13: 75.8: 19.28
+	Hs
		297856 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		SC24D_HUMAN (951-1204): 5.56e-13: 75.7: 25.44
+	Hs
		967541 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		PCLO_HUMAN (641-1108): 1.55e-10: 68.2: 11.90
+	Hs
		118625 EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		118520 EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		318751 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		ZMIZ1_HUMAN (968-1213): 2.22e-11: 70.8: 16.53