HitPredict

Interactor 1: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Interactor 2: NCOA3 (Q9Y6Q9)
Nuclear receptor coactivator 3 (NCoA-3) (EC 2.3.1.48) (ACTR) (Amplified in breast cancer 1 protein) (AIB-1) (CBP-interacting protein) (pCIP) (Class E basic helix-loop-helix protein 42) (bHLHe42) (Receptor-associated coactivator 3) (RAC-3) (Steroid receptor coactivator protein 3) (SRC-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1)
Gene: NCOA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24999758
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 656 Hs			1 1424
+	Hs
		318764 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		NCOA3_HUMAN (1-1424): 3.11e-164: 533: 100.00
+	Hs
		967389 EWS_HUMAN (1-656): 1.54e-47: 179: 100.00		EPAS1_HUMAN (12-878): 3.88e-100: 343: 13.27
+	Hs
		318623 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		NCOA2_HUMAN (1-1422): 5.82e-99: 350: 38.89
+	Hs
		318627 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		NCOA1_HUMAN (1-1353): 9.13e-76: 279: 24.53
+	Hs
		318576 EYA4_HUMAN (3-271): 6.07e-39: 154: 18.02		ARNT_HUMAN (6-642): 2.95e-76: 272: 16.01