HitPredict

Interactor 1: PO5F1 (Q01860)
POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3)
Gene: POU5F1

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26687479
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 360 Hs			1 1214
+	Mm
		590381 PO5F1_MOUSE (1-360): 5.33e-84: 260: 83.61		SMRC2_MOUSE (1-1203): 0: 957: 96.51
+	Mm
		590299 PO5F1_MOUSE (1-360): 5.33e-84: 260: 83.61		SMRC1_MOUSE (4-1028): 0: 952: 64.13
+	Hs
		839788 LHX2_HUMAN (209-359): 5.35e-39: 145: 21.71		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		839796 LHX2_HUMAN (209-359): 5.35e-39: 145: 21.71		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Dm
		950058 UBX_DROME (41-290): 1.3e-36: 138: 20.87		Q9VF03_DROME (5-1126): 0: 723: 40.84
+	Mm
		590390 PO5F1_MOUSE (1-360): 5.33e-84: 260: 83.61		KDM1A_MOUSE (254-543): 9.03e-44: 174: 15.05
+	Hs
		968023 PO5F1_HUMAN (1-360): 7.32e-89: 273: 100.00		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Mm
		959179 PIT1_MOUSE (68-295): 1.09e-54: 183: 36.44		KDM1A_MOUSE (254-543): 9.03e-44: 174: 15.05
+	Mm
		590420 PO5F1_MOUSE (1-360): 5.33e-84: 260: 83.61		KMT2C_MOUSE (646-1214): 4.14e-10: 66.6: 8.22
+	Hs
		261411 PIT1_HUMAN (29-295): 4.51e-56: 186: 32.36		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		159955 PO6F2_HUMAN (3-300): 9.36e-36: 139: 22.65		HGS_HUMAN (668-1181): 1.12e-46: 182: 19.20
+	Hs
		232050 HXA1_HUMAN (62-302): 1.69e-34: 131: 17.28		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		540885 PO2F1_HUMAN (65-359): 5.12e-40: 152: 32.80		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		839855 LHX2_HUMAN (209-359): 5.35e-39: 145: 21.71		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261442 LHX2_HUMAN (209-359): 5.35e-39: 145: 21.71		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Hs
		232284 ZFHX4_HUMAN (2-287): 7.2e-12: 68.9: 14.53		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		839785 LHX2_HUMAN (209-359): 5.35e-39: 145: 21.71		KMT2C_HUMAN (650-1128): 8.15e-09: 62.4: 8.57