HitPredict

Interactor 1: OCRL (Q01968)
Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86)
Gene: OCRL

Interactor 2: AP1B1 (Q10567)
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)
Gene: AP1B1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25107275
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 901 Hs			1 949
+	Hs
		925855 OCRL_HUMAN (1-901): 0: 1075: 100.00		AP2B1_HUMAN (1-949): 0: 944: 81.45
+	Hs
		321531 OCRL_HUMAN (1-901): 0: 1075: 100.00		AP2A1_HUMAN (12-943): 0: 677: 18.58
+	Hs
		302140 OCRL_HUMAN (1-901): 0: 1075: 100.00		AP2A2_HUMAN (12-945): 0: 625: 18.33
+	Hs
		212621 OCRL_HUMAN (1-901): 0: 1075: 100.00		AP1G1_HUMAN (12-822): 0: 556: 17.29
+	Hs
		203223 SYNJ1_HUMAN (218-733): 8.18e-121: 403: 24.37		AP1B1_HUMAN (1-949): 0: 978: 100.00
+	Hs
		203219 SYNJ1_HUMAN (218-733): 8.18e-121: 403: 24.37		AP2B1_HUMAN (1-949): 0: 944: 81.45
+	Hs
		203194 SYNJ1_HUMAN (218-733): 8.18e-121: 403: 24.37		AP2A1_HUMAN (12-943): 0: 677: 18.58
+	Rn
		1144064 SYNJ1_RAT (218-738): 2.76e-120: 401: 24.79		Q66HM2_RAT (12-945): 0: 631: 17.92
+	Sc
		730448 INP53_YEAST (215-556): 1.77e-110: 367: 30.75		AP1B1_YEAST (12-705): 9.09e-171: 517: 36.31