HitPredict

Interactor 1: MTD1 (Q02046)
Methylenetetrahydrofolate dehydrogenase [NAD(+)] (EC 1.5.1.15)
Gene: MTD1

Interactor 2: MTD1 (Q02046)
Methylenetetrahydrofolate dehydrogenase [NAD(+)] (EC 1.5.1.15)
Gene: MTD1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.786

The method score is based on:

Property Details
Experiments 18467557, 10933503
Identification Methods protein complementation assay, x-ray crystallography, dihydrofolate reductase reconstruction
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains THF_DHG_CYH~THF_DHG_CYH, THF_DHG_CYH~THF_DHG_CYH_C, THF_DHG_CYH_C~THF_DHG_CYH_C
Common GO terms GO:0004477 - methenyltetrahydrofolate cyclohydrolase activity
GO:0004487 - methylenetetrahydrofolate dehydrogenase (NAD+) activity
GO:0004488 - methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005634 - nucleus
GO:0005829 - cytosol
and 5 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 320
Sc

1 320
+ Sp
+ Sc
+ Hs
+ Sc
+ Cj

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024