Interactor 1: ACTI1 (Q02059)
Actinorhodin polyketide putative beta-ketoacyl synthase 1 (EC 2.3.1.-) (actI ORF1)
Gene: SCO5087

Interactor 2: ACTI2 (Q02062)
Actinorhodin polyketide putative beta-ketoacyl synthase 2 (EC 2.3.1.-) (actI ORF2)
Gene: SCO5088

Species: Streptomyces coelicolor A3(2)

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 15286722
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ketoacyl-synt~ketoacyl-synt, Ketoacyl-synt_C~ketoacyl-synt, Ketoacyl-synt_C~Ketoacyl-synt_C
Common GO terms GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0006633 - fatty acid biosynthetic process
GO:0017000 - antibiotic biosynthetic process
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 467
Sc

1 407
+ Bs
+ Ec
+ Rn
+ Hs
+ Ss
+ Ec
+ Mt
+ Mt
+ Pa
+ Mt
+ Bs
+ Sc

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Last updated: 15 Jul 2024