HitPredict

Interactor 1: SP2 (Q02086)
Transcription factor Sp2
Gene: SP2

Interactor 2: NR0B2 (Q15466)
Nuclear receptor subfamily 0 group B member 2 (Orphan nuclear receptor SHP) (Small heterodimer partner)
Gene: NR0B2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17071613
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 613 Hs			1 257
+	Hs
		823901 SP2_HUMAN (1-607): 6.44e-142: 427: 100.00		NR2C2_HUMAN (33-256): 6.58e-59: 198: 25.89
+	Mm
		292662 SP1_MOUSE (28-611): 4.3e-98: 318: 28.76		NR0B1_MOUSE (44-254): 6.11e-74: 234: 34.51
+	Hs
		434909 SP1_HUMAN (28-611): 1.59e-95: 311: 29.47		COT1_HUMAN (1-255): 1.8e-75: 236: 28.19
+	Hs
		434936 SP1_HUMAN (28-611): 1.59e-95: 311: 29.47		RXRA_HUMAN (20-254): 4.48e-68: 219: 22.13
+	Hs
		434993 SP1_HUMAN (28-611): 1.59e-95: 311: 29.47		HNF4A_HUMAN (14-256): 1.42e-62: 205: 23.46
+	Hs
		435030 SP1_HUMAN (28-611): 1.59e-95: 311: 29.47		ERR3_HUMAN (6-257): 1.33e-60: 199: 17.86
+	Hs
		320156 SP1_HUMAN (28-611): 1.59e-95: 311: 29.47		ERR2_HUMAN (1-257): 2.45e-60: 198: 17.12
+	Hs
		434908 SP1_HUMAN (28-611): 1.59e-95: 311: 29.47		RARA_HUMAN (49-254): 9.48e-54: 181: 17.48
+	Hs
		435194 SP1_HUMAN (28-611): 1.59e-95: 311: 29.47		NR2E1_HUMAN (5-255): 4.43e-52: 175: 24.27
+	Hs
		316822 KLF8_HUMAN (293-607): 7.05e-71: 234: 26.27		NR2C2_HUMAN (33-256): 6.58e-59: 198: 25.89
+	Hs
		316777 KLF8_HUMAN (293-607): 7.05e-71: 234: 26.27		NR2C1_HUMAN (1-256): 9.99e-57: 192: 23.49
+	Hs
		824153 ZN546_HUMAN (227-498): 3.27e-61: 219: 6.80		NR2C2_HUMAN (33-256): 6.58e-59: 198: 25.89
+	Dm
		558438 Q8IRM5_DROME (496-612): 2.02e-41: 159: 64.52		7UP1_DROME (19-255): 1.5e-71: 230: 27.43
+	Dm
		116477 M9PJG1_DROME (496-612): 1.32e-38: 153: 64.52		7UP1_DROME (19-255): 1.5e-71: 230: 27.43
+	Hs
		782648 ZN471_HUMAN (534-613): 5.18e-33: 136: 38.75		HNF4A_HUMAN (14-256): 1.42e-62: 205: 23.46
+	Mm
		793611 SP7_MOUSE (502-607): 2.44e-33: 134: 61.82		NR2F6_MOUSE (2-255): 3.68e-60: 196: 28.74
+	Hs
		824350 KLF16_HUMAN (523-607): 3.15e-30: 121: 61.18		NR2C2_HUMAN (33-256): 6.58e-59: 198: 25.89
+	Hs
		823988 KLF9_HUMAN (522-607): 1.49e-28: 116: 61.63		NR2C2_HUMAN (33-256): 6.58e-59: 198: 25.89
+	Hs
		525332 KLF16_HUMAN (523-607): 3.15e-30: 121: 61.18		NR2C1_HUMAN (1-256): 9.99e-57: 192: 23.49
+	Hs
		525311 KLF9_HUMAN (522-607): 1.49e-28: 116: 61.63		NR2C1_HUMAN (1-256): 9.99e-57: 192: 23.49