HitPredict

Interactor 1: RSC4 (Q02206)
Chromatin structure-remodeling complex subunit RSC4 (RSC complex subunit RSC4) (Remodel the structure of chromatin complex subunit 4)
Gene: RSC4

Interactor 2: SFH1 (Q06168)
Chromatin structure-remodeling complex subunit SFH1 (RSC complex subunit SFH1) (SNF5 homolog 1)
Gene: SFH1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.744

Property	Details
Experiments	16429126, 21701592, 14729968, 16554755, 37968396, 14759368, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0006337 - nucleosome disassembly GO:0006338 - chromatin remodeling GO:0006368 - transcription elongation by RNA polymerase II GO:0016586 - RSC-type complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 625 Sc			1 426
+	Sc
		728762 BDF1_YEAST (117-384): 5.12e-22: 102: 15.22		SFH1_YEAST (1-426): 0: 644: 100.00
+	Sc
		986312 BDF2_YEAST (6-210): 9.77e-18: 89.2: 14.29		SFH1_YEAST (1-426): 0: 644: 100.00
+	Sc
		986309 RSC2_YEAST (55-196): 1.71e-13: 76.1: 19.01		SFH1_YEAST (1-426): 0: 644: 100.00
+	Sc
		860447 RSC1_YEAST (58-176): 2.04e-11: 69.2: 21.01		SFH1_YEAST (1-426): 0: 644: 100.00
+	Hs
		1017159 PB1_HUMAN (24-312): 2.23e-43: 169: 18.37		SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87
+	Dm
		631293 BRM_DROME (166-291): 1.07e-32: 137: 29.37		Q24090_DROME (187-407): 4.45e-100: 304: 27.48
+	Mm
		1150297 SMCA2_MOUSE (56-148): 4.3e-14: 78.2: 32.32		SNF5_MOUSE (174-407): 4.27e-104: 315: 27.87
+	Hs
		1017195 CBP_HUMAN (2-161): 8.96e-14: 77.2: 17.06		SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87
+	Mm
		1111974 SMCA4_MOUSE (56-148): 2.07e-12: 72.8: 33.33		SNF5_MOUSE (174-407): 4.27e-104: 315: 27.87
+	Rn
		1117300 SMCA4_RAT (56-148): 2.05e-12: 72.8: 33.33		Q4KLI0_RAT (174-407): 2.7e-104: 315: 27.87
+	Hs
		846949 SMCA4_HUMAN (56-148): 3.01e-12: 72.1: 33.00		SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87
+	Hs
		846761 SMCA2_HUMAN (78-148): 9.33e-12: 70.5: 34.72		SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87
+	Hs
		244353 BRD4_HUMAN (79-180): 1.04e-11: 70.2: 19.05		SNF5_HUMAN (174-407): 4.27e-104: 315: 27.87
+	Sc
		577174 GCN5_YEAST (5-160): 4.11e-20: 95.3: 16.77		SNF5_YEAST (177-382): 6.44e-64: 222: 25.34