Interactor 1: ODO1 (Q02218)
2-oxoglutarate dehydrogenase complex component E1 (E1o) (OGDC-E1) (OGDH-E1) (EC 1.2.4.2) (2-oxoglutarate dehydrogenase, mitochondrial) (Alpha-ketoglutarate dehydrogenase) (Alpha-KGDH-E1) (Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase)
Gene: OGDH

Interactor 2: OGDHL (Q9ULD0)
2-oxoglutarate dehydrogenase-like, mitochondrial (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1-like) (OGDC-E1-like) (Alpha-ketoglutarate dehydrogenase-like)
Gene: OGDHL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains E1_dh~E1_dh, E1_dh~OxoGdeHyase_C, E1_dh~Transket_pyr, OxoGdeHyase_C~OxoGdeHyase_C, OxoGdeHyase_C~Transket_pyr, Transket_pyr~Transket_pyr
Common GO terms GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006096 - glycolytic process
GO:0006099 - tricarboxylic acid cycle
and 4 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1023
Hs

1 1010
+ Sc
+ Ec
+ Hs
+ Sc
+ Hs
+ At

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Last updated: 15 Jul 2024