HitPredict

Interactor 1: CENPE (Q02224)
Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-7) (Kinesin-related protein CENPE)
Gene: CENPE

Interactor 2: NUF2 (Q9BZD4)
Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1)
Gene: NUF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.642

The method score is based on:

Property Details
Experiments 19779646, 17535814
Identification Methods two hybrid, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005829 - cytosol
GO:0007052 - mitotic spindle organization
GO:0007059 - chromosome segregation
GO:0008017 - microtubule binding
and 3 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 2701
Hs

1 464
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024