HitPredict

Interactor 1: CTNB1 (Q02248)
Catenin beta-1 (Beta-catenin)
Gene: Ctnnb1

Interactor 2: KC1E (Q9JMK2)
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)
Gene: Csnk1e

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	17053159, 15327768, 12417018
Identification Methods	affinity chromatography technology, enzymatic study, in-gel kinase assay
Interaction Type	physical association, direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0008104 - protein localization GO:0060070 - canonical Wnt signaling pathway
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 781 Mm			1 416
+	Hs
		716874 CTNB1_HUMAN (1-781): 0: 650: 99.87		KC1E_HUMAN (1-416): 6.6e-136: 397: 98.80
+	Hs
		681690 CTNB1_HUMAN (1-781): 0: 650: 99.87		AKT1_HUMAN (5-357): 3.64e-120: 359: 18.51
+	Hs
		682139 CTNB1_HUMAN (1-781): 0: 650: 99.87		AKT2_HUMAN (5-357): 2.96e-120: 359: 18.28
+	Hs
		716870 CTNB1_HUMAN (1-781): 0: 650: 99.87		KC1A_HUMAN (2-327): 2.56e-121: 357: 69.02
+	Dm
		578625 ARM_DROME (25-780): 2.58e-163: 495: 67.00		KC1A_DROME (2-320): 1.91e-123: 362: 65.11
+	Hs
		821950 IMA5_HUMAN (433-674): 2.13e-22: 103: 13.91		KC1A_HUMAN (2-327): 2.56e-121: 357: 69.02
+	Dm
		1213379 Q9V455_DROME (457-668): 3.16e-13: 74.9: 16.03		AKT1_DROME (1-332): 7.7e-119: 360: 17.94