Interactor 1: FNTB (Q02293)
Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta)
Gene: FNTB

Interactor 2: FNTA (Q04631)
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (EC 2.5.1.58) (EC 2.5.1.59) (CAAX farnesyltransferase subunit alpha) (FTase-alpha) (Ras proteins prenyltransferase subunit alpha) (Type I protein geranyl-geranyltransferase subunit alpha) (GGTase-I-alpha)
Gene: FNTA

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 9657673, 9065406, 12657282, 12667062, 12699757, 15170324, 10377218, 12657283, 12657284
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PPTA~Prenyltrans
Common GO terms GO:0004660 - protein farnesyltransferase activity
GO:0005875 - microtubule associated complex
GO:0005965 - protein farnesyltransferase complex
GO:0008284 - positive regulation of cell population proliferation
GO:0014070 - response to organic cyclic compound
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 437
Rn

1 377
+ Hs
+ Hs
+ Rn
+ Dm
+ Ce
+ At
+ Sp
+ Sc
+ Ce
+ At
+ Hs
+ Rn
+ Sc
+ Dm
+ Sp
+ Dm
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024