HitPredict

Interactor 1: CDK5 (Q02399)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Proline-directed protein kinase 33 kDa subunit) (PDPK) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Interactor 2: PCNA (Q3ZBW4)
Proliferating cell nuclear antigen (PCNA)
Gene: PCNA

Species: Bos taurus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	9396813
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 292 Bt			1 261
+	Bt
		1114085 CDK2_BOVIN (1-292): 1.21e-144: 410: 59.73		PCNA_BOVIN (1-261): 1.23e-126: 361: 100.00
+	Hs
		517061 CDK2_HUMAN (1-292): 3.69e-144: 408: 59.39		PCNA_HUMAN (1-261): 4e-126: 360: 99.23
+	Hs
		517199 CDK5_HUMAN (1-292): 9.9e-140: 397: 99.66		PCNA_HUMAN (1-261): 4e-126: 360: 99.23
+	Mm
		572245 CDK2_MOUSE (1-292): 1.25e-136: 391: 51.77		PCNA_MOUSE (1-261): 2.08e-127: 363: 96.94
+	Hs
		414703 CDK1_HUMAN (1-289): 3.28e-135: 385: 56.01		PCNA_HUMAN (1-261): 4e-126: 360: 99.23
+	Hs
		517133 CDK7_HUMAN (2-292): 1.3e-126: 366: 45.24		PCNA_HUMAN (1-261): 4e-126: 360: 99.23