Interactor 1: DSG1 (Q02413)
Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)
Gene: DSG1

Interactor 2: DSC1 (Q08554)
Desmocollin-1 (Cadherin family member 1) (Desmosomal glycoprotein 2/3) (DG2/DG3)
Gene: DSC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 24981860, 9606214, 19136012
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cadherin~Cadherin
Common GO terms GO:0001533 - cornified envelope
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007043 - cell-cell junction assembly
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
and 4 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1049
Hs

1 894
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024