HitPredict

Interactor 1: DSG1 (Q02413)
Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)
Gene: DSG1

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31300519
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0050821 - protein stabilization
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1049 Hs			1 581
+	Hs
		681797 DSG1_HUMAN (1-1049): 0: 1147: 100.00		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		970859 DSG1_HUMAN (1-1049): 0: 1147: 100.00		KCC2A_HUMAN (221-538): 5.11e-82: 266: 20.62
+	Hs
		1048653 DSG2_HUMAN (2-1048): 0: 742: 32.40		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		701695 DSG3_HUMAN (1-896): 0: 664: 39.76		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1048588 DSG2_HUMAN (2-1048): 0: 742: 32.40		KS6A2_HUMAN (197-576): 4.99e-92: 300: 15.42
+	Hs
		996007 DSC1_HUMAN (29-765): 0: 574: 24.87		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Xl
		292722 O93264_XENLA (19-509): 1.92e-82: 286: 16.63		AKT1_XENLA (115-573): 7.09e-121: 367: 13.90
+	Hs
		1055851 DSC3_HUMAN (1-355): 3.07e-35: 147: 20.27		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		971059 DSC2_HUMAN (1-378): 2.26e-32: 138: 18.73		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		521749 CADH1_HUMAN (19-485): 8.8e-59: 220: 19.01		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		521711 CADH1_HUMAN (19-485): 8.8e-59: 220: 19.01		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		522043 CADH1_HUMAN (19-485): 8.8e-59: 220: 19.01		KCC1D_HUMAN (204-577): 2.56e-101: 313: 16.75