HitPredict

Interactor 1: H11 (Q02539)
Histone H1.1 (Histone H1a)
Gene: H1-1

Interactor 2: NSD3 (Q9BZ95)
Histone-lysine N-methyltransferase NSD3 (EC 2.1.1.370) (EC 2.1.1.371) (Nuclear SET domain-containing protein 3) (Protein whistle) (WHSC1-like 1 isoform 9 with methyltransferase activity to lysine) (Wolf-Hirschhorn syndrome candidate 1-like protein 1) (WHSC1-like protein 1)
Gene: NSD3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23455924
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 1437
+	Hs
		331717 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		NSD2_HUMAN (140-1414): 0: 825: 45.08
+	Hs
		331716 H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88		NSD2_HUMAN (140-1414): 0: 825: 45.08
+	Hs
		331706 H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76		NSD2_HUMAN (140-1414): 0: 825: 45.08
+	Hs
		331791 H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00		NSD2_HUMAN (140-1414): 0: 825: 45.08
+	Hs
		559937 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		ZCPW1_HUMAN (184-595): 3.45e-77: 271: 17.45
+	Mm
		990819 H1T_MOUSE (1-213): 1.33e-39: 136: 49.30		EZH2_MOUSE (1076-1270): 1.26e-58: 218: 28.78
+	Hs
		559417 H13_HUMAN (1-169): 5.79e-27: 104: 55.03		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		489204 H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76		EHMT2_HUMAN (1029-1281): 2.28e-60: 229: 22.84
+	Hs
		971310 H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00		EHMT2_HUMAN (1029-1281): 2.28e-60: 229: 22.84
+	Hs
		559730 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		559109 H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		971187 H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		559663 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		KMT2A_HUMAN (1131-1285): 7.1e-40: 164: 30.13
+	Hs
		489011 H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76		KMT2A_HUMAN (1131-1285): 7.1e-40: 164: 30.13
+	Hs
		559470 H13_HUMAN (1-169): 5.79e-27: 104: 55.03		NSD1_HUMAN (91-724): 2.53e-28: 126: 15.30
+	Hs
		559895 H12_HUMAN (32-175): 4.83e-23: 94: 54.86		NSD1_HUMAN (91-724): 2.53e-28: 126: 15.30
+	Hs
		559217 H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88		NSD1_HUMAN (91-724): 2.53e-28: 126: 15.30
+	Hs
		489205 H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76		NSD1_HUMAN (91-724): 2.53e-28: 126: 15.30