HitPredict

Interactor 1: IRF8 (Q02556)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP)
Gene: IRF8

Interactor 2: IFNL1 (Q8IU54)
Interferon lambda-1 (IFN-lambda-1) (Cytokine Zcyto21) (Interleukin-29) (IL-29)
Gene: IFNL1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17785777
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032729 - positive regulation of type II interferon production
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 200
+	Hs
		971741 IRF8_HUMAN (1-426): 0: 587: 100.00		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		1056433 IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		1056436 IRF3_HUMAN (9-399): 1.44e-139: 407: 26.68		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		1215834 IRF7_HUMAN (12-385): 3.06e-114: 345: 21.91		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		1224458 IRF7_HUMAN (12-385): 3.06e-114: 345: 21.91		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		501063 IRF1_HUMAN (9-187): 2.59e-62: 206: 33.69		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		501067 IRF1_HUMAN (9-187): 2.59e-62: 206: 33.69		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94