Interactor 1: CACB1 (Q02641)
Voltage-dependent L-type calcium channel subunit beta-1 (CAB1) (Calcium channel voltage-dependent subunit beta 1)
Gene: CACNB1

Interactor 2: CACB2 (Q08289)
Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB)
Gene: CACNB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~Guanylate_kin, Guanylate_kin~VGCC_beta4Aa_N
Common GO terms GO:0005245 - voltage-gated calcium channel activity
GO:0005886 - plasma membrane
GO:0005891 - voltage-gated calcium channel complex
GO:0007268 - chemical synaptic transmission
GO:0007528 - neuromuscular junction development
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 598
Hs

1 660
+ Rn
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024