Interactor 1: TIE2 (Q02763)
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)
Gene: TEK

Interactor 2: ANGP4 (Q9Y264)
Angiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3)
Gene: ANGPT4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.602

The method score is based on:

Property Details
Experiments 10051567, 20708158
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001525 - angiogenesis
GO:0005576 - extracellular region
GO:0010595 - positive regulation of endothelial cell migration
GO:0016525 - negative regulation of angiogenesis
GO:0043066 - negative regulation of apoptotic process
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 1124
Hs

1 503
+ Hs
+ Hs
+ Hs
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+ Hs

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Last updated: 15 Jul 2024