HitPredict

Interactor 1: PLOD1 (Q02809)
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1)
Gene: PLOD1

Interactor 2: COPA1 (Q9BXS0)
Collagen alpha-1(XXV) chain (Alzheimer disease amyloid-associated protein) (AMY) (CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component (CLAC)]
Gene: COL25A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 727 Hs			1 654
+	Hs
		358604 PLOD1_HUMAN (1-727): 0: 1245: 100.00		CO2A1_HUMAN (234-653): 1.44e-31: 133: 34.69
+	Hs
		972805 PLOD1_HUMAN (1-727): 0: 1245: 100.00		COLA1_HUMAN (428-653): 3.41e-27: 119: 36.63
+	Hs
		972738 PLOD1_HUMAN (1-727): 0: 1245: 100.00		CO4A6_HUMAN (308-646): 7.42e-21: 99.9: 29.80
+	Hs
		972776 PLOD1_HUMAN (1-727): 0: 1245: 100.00		CONA1_HUMAN (35-536): 1.21e-20: 97.8: 40.80
+	Hs
		358661 PLOD1_HUMAN (1-727): 0: 1245: 100.00		CO4A1_HUMAN (3-358): 3.55e-18: 91.4: 29.36
+	Hs
		129937 PLOD2_HUMAN (13-727): 0: 1209: 60.06		COLA1_HUMAN (428-653): 3.41e-27: 119: 36.63
+	Hs
		358499 PLOD1_HUMAN (1-727): 0: 1245: 100.00		CO1A1_HUMAN (53-274): 1.38e-14: 79.8: 30.63
+	Hs
		517941 PLOD1_HUMAN (1-727): 0: 1245: 100.00		CO6A1_HUMAN (123-365): 7.74e-14: 77: 35.85
+	Hs
		517998 PLOD1_HUMAN (1-727): 0: 1245: 100.00		CO6A2_HUMAN (568-651): 1.7e-12: 72.9: 32.00
+	Hs
		68474 PLOD1_HUMAN (1-727): 0: 1245: 100.00		A8MWQ5_HUMAN (70-174): 1.08e-09: 63.7: 28.57
+	Hs
		129925 PLOD2_HUMAN (13-727): 0: 1209: 60.06		CONA1_HUMAN (35-536): 1.21e-20: 97.8: 40.80
+	Hs
		441060 PLOD1_HUMAN (1-727): 0: 1245: 100.00		CO4A2_HUMAN (8-180): 5.19e-09: 61.7: 16.76
+	Hs
		237052 PLOD3_HUMAN (21-727): 0: 1195: 59.38		CO4A6_HUMAN (308-646): 7.42e-21: 99.9: 29.80
+	Hs
		129876 PLOD2_HUMAN (13-727): 0: 1209: 60.06		CO1A1_HUMAN (53-274): 1.38e-14: 79.8: 30.63
+	Hs
		237006 PLOD3_HUMAN (21-727): 0: 1195: 59.38		CO4A1_HUMAN (3-358): 3.55e-18: 91.4: 29.36
+	Hs
		129885 PLOD2_HUMAN (13-727): 0: 1209: 60.06		CO6A2_HUMAN (568-651): 1.7e-12: 72.9: 32.00
+	Hs
		237005 PLOD3_HUMAN (21-727): 0: 1195: 59.38		CO1A1_HUMAN (53-274): 1.38e-14: 79.8: 30.63
+	Hs
		237019 PLOD3_HUMAN (21-727): 0: 1195: 59.38		CO6A1_HUMAN (123-365): 7.74e-14: 77: 35.85
+	Hs
		237020 PLOD3_HUMAN (21-727): 0: 1195: 59.38		CO6A2_HUMAN (568-651): 1.7e-12: 72.9: 32.00
+	Hs
		237016 PLOD3_HUMAN (21-727): 0: 1195: 59.38		CO4A2_HUMAN (8-180): 5.19e-09: 61.7: 16.76