HitPredict

Interactor 1: IMA1 (Q02821)
Importin subunit alpha (Karyopherin subunit alpha) (Karyopherin-60) (Serine-rich RNA polymerase I suppressor protein)
Gene: SRP1

Interactor 2: IMB1 (Q06142)
Importin subunit beta-1 (Importin-95) (Karyopherin subunit beta-1) (Karyopherin-95)
Gene: KAP95

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 11535617, 19098896, 16615907, 9321403, 11805837, 25838545, 8849456, 9412460, 9744791, 16554755, 16429126, 19549784, 37968396, 14759368, 11425876, 9151683, 11867631, 7622450, 12543930, 12486120 and 2 others

more...
Identification Methods affinity chromatography technology, molecular sieving, comigration in non denaturing gel electrophoresis, protease accessibility laddering, anti tag coimmunoprecipitation, two hybrid, pull down, biochemical, tandem affinity purification, far western blotting
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT_EZ~IBB, IBB~IBN_N
Common GO terms GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus
and 8 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 542
Sc

1 861
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Sp
+ Hs
+ Hs
+ Dm
+ Dm
+ Sc
+ Hs
+ Hs
+ Hs
+ Sp
+ Xl
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024