HitPredict

Interactor 1: IMA1 (Q02821)
Importin subunit alpha (Karyopherin subunit alpha) (Karyopherin-60) (Serine-rich RNA polymerase I suppressor protein)
Gene: SRP1

Interactor 2: NOP58 (Q12499)
Nucleolar protein 58 (Nucleolar protein 5)
Gene: NOP58

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	16554755, 14759368
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 542 Sc			1 511
+	Hs
		133254 IMA7_HUMAN (6-541): 1.46e-143: 426: 50.37		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		133234 IMA3_HUMAN (8-541): 2.87e-143: 424: 45.07		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		131337 IMA4_HUMAN (8-541): 4.18e-142: 421: 44.90		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		238749 IMA7_HUMAN (6-541): 1.46e-143: 426: 50.37		NOP58_HUMAN (2-506): 0: 546: 45.69
+	Sp
		293205 IMA2_SCHPO (8-542): 1.03e-146: 434: 56.43		NOP56_SCHPO (3-452): 0: 534: 39.83
+	Hs
		853524 IMA1_HUMAN (6-541): 1.45e-141: 420: 44.02		NOP58_HUMAN (2-506): 0: 546: 45.69
+	Sc
		972944 IMA1_YEAST (1-542): 2.38e-161: 471: 100.00		NOP56_YEAST (1-473): 1.17e-170: 493: 37.58
+	Hs
		133237 IMA6_HUMAN (6-541): 4.04e-136: 407: 49.35		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		133392 IMA5_HUMAN (8-541): 1.74e-135: 405: 48.61		NOP56_HUMAN (1-511): 0: 551: 37.55
+	Hs
		853761 IMA5_HUMAN (8-541): 1.74e-135: 405: 48.61		NOP58_HUMAN (2-506): 0: 546: 45.69
+	Hs
		853397 IMA1_HUMAN (6-541): 1.45e-141: 420: 44.02		PRP31_HUMAN (155-454): 6.6e-105: 324: 22.08
+	Hs
		853666 IMA5_HUMAN (8-541): 1.74e-135: 405: 48.61		PRP31_HUMAN (155-454): 6.6e-105: 324: 22.08