HitPredict

Interactor 1: NOG1 (Q02892)
Nucleolar GTP-binding protein 1
Gene: NOG1

Interactor 2: ERB1 (Q04660)
Ribosome biogenesis protein ERB1 (Eukaryotic ribosome biogenesis protein 1)
Gene: ERB1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.745

Property	Details
Experiments	11805837, 37968396, 12808088, 16429126, 16888624, 29294095, 23874617
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030687 - preribosome, large subunit precursor GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 647 Sc			1 807
+	Dm
		1178808 NOG1_DROME (3-647): 0: 577: 47.13		BOP1_DROME (9-806): 1e-174: 524: 36.92
+	Hs
		903493 GTPB4_HUMAN (2-647): 0: 653: 46.06		WDR5_HUMAN (330-665): 7.13e-47: 172: 11.53
+	Hs
		1317904 GTPB4_HUMAN (2-647): 0: 653: 46.06		NLE1_HUMAN (706-806): 8.16e-21: 98.6: 17.82
+	Sc
		630885 NOG1_YEAST (1-647): 0: 628: 100.00		NLE1_YEAST (676-807): 3.44e-28: 121: 16.43
+	Hs
		1281371 GTPB4_HUMAN (2-647): 0: 653: 46.06		FBXW7_HUMAN (717-807): 4.36e-11: 68.6: 22.83
+	Hs
		903619 DRG1_HUMAN (98-494): 3.82e-81: 262: 14.22		WDR5_HUMAN (330-665): 7.13e-47: 172: 11.53
+	Hs
		1281489 DRG1_HUMAN (98-494): 3.82e-81: 262: 14.22		FBXW7_HUMAN (717-807): 4.36e-11: 68.6: 22.83