HitPredict

Interactor 1: CREB5 (Q02930)
Cyclic AMP-responsive element-binding protein 5 (CREB-5) (cAMP-responsive element-binding protein 5) (cAMP-response element-binding protein A) (CRE-BPa)
Gene: CREB5

Interactor 2: Q6FG41 (Q6FG41)
Protein c-Fos (Cellular oncogene fos)
Gene: FOS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	bZIP_1~bZIP_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 508 Hs			1 380
+	Hs
		345402 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		FOS_HUMAN (1-380): 1.68e-84: 263: 100.00
+	Mm
		345623 ATF7_MOUSE (10-456): 1.31e-76: 248: 35.94		FOS_MOUSE (1-380): 1.27e-84: 263: 93.68
+	Hs
		345313 ATF7_HUMAN (10-505): 4.77e-72: 238: 36.18		FOS_HUMAN (1-380): 1.68e-84: 263: 100.00
+	Hs
		973637 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		BACH2_HUMAN (14-307): 4.1e-34: 136: 13.65
+	Hs
		548238 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61
+	Hs
		157199 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		BACH1_HUMAN (4-295): 1.68e-30: 125: 12.99
+	Hs
		568260 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		ATF7_HUMAN (82-289): 7.9e-31: 124: 16.59
+	Hs
		548298 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		FOSL2_HUMAN (2-380): 3.19e-31: 122: 39.54
+	Hs
		547788 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57
+	Hs
		862613 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		FOSB_HUMAN (2-380): 1.59e-25: 107: 34.24
+	Hs
		973553 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		CREB5_HUMAN (92-233): 1.13e-24: 107: 19.01
+	Hs
		973646 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		BATF3_HUMAN (120-228): 1.45e-27: 107: 27.52
+	Hs
		566750 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		JUNB_HUMAN (85-215): 3.19e-25: 106: 19.86
+	Hs
		401872 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		JUN_HUMAN (48-215): 1.19e-23: 102: 16.47
+	Hs
		973609 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		JDP2_HUMAN (147-220): 1.47e-21: 92: 37.84
+	Hs
		568088 CREB5_HUMAN (1-508): 3.92e-104: 322: 100.00		JUND_HUMAN (112-215): 1.79e-13: 72.8: 20.00
+	Hs
		548216 ATF7_HUMAN (10-505): 4.77e-72: 238: 36.18		FOSL1_HUMAN (59-287): 1.43e-34: 130: 37.61
+	Hs
		157176 ATF7_HUMAN (10-505): 4.77e-72: 238: 36.18		BACH1_HUMAN (4-295): 1.68e-30: 125: 12.99
+	Hs
		547688 ATF7_HUMAN (10-505): 4.77e-72: 238: 36.18		ATF2_HUMAN (4-283): 3.58e-29: 119: 18.57
+	Hs
		401377 ATF7_HUMAN (10-505): 4.77e-72: 238: 36.18		JUN_HUMAN (48-215): 1.19e-23: 102: 16.47