Interactor 1: HH (Q02936)
Protein hedgehog (EC 3.1.-.-) [Cleaved into: Protein hedgehog N-product (Hh-Np) (N-Hh)]
Gene: HH
Interactor 2: IHOG (Q9VM64)
Interference hedgehog
Gene: IHOG
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16630821, 20048000, 17348690, 17077139, 21828006, 20231458, 18794898 |
| Identification Methods | affinity chromatography technology, pull down, x-ray crystallography, cosedimentation in solution, molecular sieving, isothermal titration calorimetry, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HH_signal~fn3 |
| Common GO terms | GO:0005113 - patched binding GO:0005886 - plasma membrane GO:0007224 - smoothened signaling pathway GO:0035222 - wing disc pattern formation GO:0048100 - wing disc anterior/posterior pattern formation |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Dm |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
 |
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
