Interactor 1: HH (Q02936)
Protein hedgehog (EC 3.1.-.-) [Cleaved into: Protein hedgehog N-product (Hh-Np) (N-Hh)]
Gene: HH

Interactor 2: DISP (Q9VNJ5)
Protein dispatched
Gene: DISP

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.814

The method score is based on:

Property Details
Experiments 21690386, 32494603, unassigned4
Identification Methods affinity chromatography technology, pull down, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HH_signal~Patched
Common GO terms GO:0005886 - plasma membrane
GO:0007224 - smoothened signaling pathway
GO:0007367 - segment polarity determination
GO:0035222 - wing disc pattern formation
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 471
Dm

1 1218
+ Dm
+ Hs
+ Mm

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Last updated: 15 Jul 2024