HitPredict

Interactor 1: AKA12 (Q02952)
A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen)
Gene: AKAP12

Interactor 2: DYR1A (Q13627)
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.11.23) (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
Gene: DYRK1A

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1782 Hs			1 763
+	Hs
		973780 AKA12_HUMAN (1-1782): 0: 676: 100.00		DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53
+	Hs
		414875 AKA12_HUMAN (1-1782): 0: 676: 100.00		CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57
+	Hs
		807717 MAP1B_HUMAN (3-1107): 1.08e-90: 331: 8.57		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		152642 KMT2D_HUMAN (47-764): 3.85e-43: 176: 11.48		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		1044321 PCLO_HUMAN (2-1636): 2.88e-35: 150: 9.87		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Ce
		103460 G4SF97_CAEEL (11-1404): 3.03e-101: 364: 7.55		MBK1_CAEEL (6-531): 1.33e-120: 385: 49.91
+	Hs
		807687 MAP1B_HUMAN (3-1107): 1.08e-90: 331: 8.57		CDK3_HUMAN (156-436): 1.81e-117: 358: 26.12
+	Hs
		801128 KI67_HUMAN (1-1782): 2.94e-11: 71.2: 11.31		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		944676 MAP1A_HUMAN (8-653): 8.53e-09: 63: 8.76		DYR1A_HUMAN (1-763): 0: 613: 100.00
+	Hs
		152597 KMT2D_HUMAN (47-764): 3.85e-43: 176: 11.48		AKT1_HUMAN (38-466): 4.44e-117: 363: 19.42
+	Ce
		246633 O61201_CAEEL (264-1678): 2.79e-21: 104: 11.73		MBK2_CAEEL (82-494): 4.42e-113: 363: 39.47
+	Hs
		1264773 TITIN_HUMAN (21-962): 3.34e-13: 77.6: 11.72		DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53
+	Hs
		1268608 SRRM2_HUMAN (4-1096): 6.49e-11: 70: 7.25		DYRK2_HUMAN (46-549): 5.03e-120: 375: 33.53
+	Hs
		414809 KI67_HUMAN (1-1782): 2.94e-11: 71.2: 11.31		CDK1_HUMAN (156-482): 1.29e-121: 368: 26.57
+	Hs
		625528 TITIN_HUMAN (21-962): 3.34e-13: 77.6: 11.72		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85
+	Hs
		625642 SRRM2_HUMAN (4-1096): 6.49e-11: 70: 7.25		CDK2_HUMAN (156-420): 1.05e-117: 358: 26.85