HitPredict

Interactor 1: AKA12 (Q02952)
A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen)
Gene: AKAP12

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1782 Hs			1 665
+	Hs
		924490 AKA12_HUMAN (1-1782): 0: 676: 100.00		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		1056926 MDC1_HUMAN (22-1697): 4.38e-13: 77: 12.50		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		1285227 SRRM2_HUMAN (4-1096): 6.49e-11: 70: 7.25		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Hs
		807680 MAP1B_HUMAN (3-1107): 1.08e-90: 331: 8.57		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		557777 MINT_HUMAN (7-1665): 1.47e-54: 213: 10.50		NCK1_HUMAN (104-421): 1.23e-32: 131: 16.81
+	Hs
		924808 MINT_HUMAN (7-1665): 1.47e-54: 213: 10.50		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		517796 NFH_HUMAN (612-1138): 3.15e-12: 73.9: 14.91		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		924760 PRG4_HUMAN (3-808): 1.87e-09: 65: 10.60		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		924473 MAP1A_HUMAN (8-653): 8.53e-09: 63: 8.76		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		801212 KI67_HUMAN (1-1782): 2.94e-11: 71.2: 11.31		DNMBP_HUMAN (104-607): 3.03e-16: 85.1: 15.82