HitPredict

Interactor 1: KPCZ (Q02956)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: Prkcz

Interactor 2: SQSTM (Q64337)
Sequestosome-1 (STONE14) (Ubiquitin-binding protein p62)
Gene: Sqstm1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26773517
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PB1~PB1, PB1~Pkinase
Common GO terms	GO:0005829 - cytosol GO:0044877 - protein-containing complex binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 592 Mm			1 442
+	Rn
		139612 KPCZ_RAT (1-592): 0: 672: 98.99		SQSTM_RAT (1-442): 0: 762: 97.06
+	Rn
		94344 KPCI_RAT (1-592): 0: 648: 69.54		SQSTM_RAT (1-442): 0: 762: 97.06
+	Hs
		983828 KPCZ_HUMAN (1-592): 0: 657: 95.61		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		784001 KPCI_HUMAN (1-592): 0: 647: 69.37		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Mm
		661009 KPCD_MOUSE (68-586): 4.08e-175: 513: 33.46		SQSTM_MOUSE (1-442): 0: 777: 100.00
+	Rn
		139610 KPCD_RAT (10-586): 1.65e-176: 517: 30.99		SQSTM_RAT (1-442): 0: 762: 97.06
+	Hs
		984491 KPCD_HUMAN (10-586): 7.31e-175: 512: 31.51		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Hs
		616709 KS6B1_HUMAN (227-590): 5.77e-145: 431: 35.60		SQSTM_HUMAN (1-442): 0: 715: 89.82
+	Rn
		139611 KPCE_RAT (6-204): 7.07e-33: 136: 18.96		SQSTM_RAT (1-442): 0: 762: 97.06
+	Rn
		139624 KPCL_RAT (6-185): 1.34e-30: 128: 24.61		SQSTM_RAT (1-442): 0: 762: 97.06
+	Rn
		139620 KPCB_RAT (101-181): 2.13e-17: 88: 30.86		SQSTM_RAT (1-442): 0: 762: 97.06
+	Rn
		139619 KPCG_RAT (116-180): 2.04e-10: 65.9: 36.92		SQSTM_RAT (1-442): 0: 762: 97.06
+	Dm
		54642 APKC_DROME (3-592): 0: 612: 61.32		REF2P_DROME (112-173): 2.24e-18: 89.4: 41.27