HitPredict

Interactor 1: HOS3 (Q02959)
Histone deacetylase HOS3 (EC 3.5.1.98)
Gene: HOS3

Interactor 2: H2AZ (Q12692)
Histone H2A.Z
Gene: HTZ1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 697 Sc			1 134
+	Sc
		392545 HOS3_YEAST (1-697): 0: 829: 100.00		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		1270389 HDAC2_HUMAN (48-600): 1.44e-139: 419: 10.81		H2A1A_HUMAN (7-134): 6e-53: 164: 55.81
+	Hs
		1087070 HDAC2_HUMAN (48-600): 1.44e-139: 419: 10.81		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		1038643 HDAC1_HUMAN (47-552): 3.39e-136: 410: 11.94		H2A1A_HUMAN (7-134): 6e-53: 164: 55.81
+	Hs
		1038464 HDAC1_HUMAN (47-552): 3.39e-136: 410: 11.94		H2A2A_HUMAN (7-133): 1.23e-51: 161: 55.47
+	Hs
		470111 HDAC2_HUMAN (48-600): 1.44e-139: 419: 10.81		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		177360 HDAC3_HUMAN (50-547): 3.34e-126: 383: 12.23		H2A1A_HUMAN (7-134): 6e-53: 164: 55.81
+	Sc
		693079 RPD3_YEAST (39-532): 9.42e-126: 382: 11.85		H2AZ_YEAST (1-134): 2.81e-53: 165: 100.00
+	Hs
		1087136 HDAC5_HUMAN (3-468): 3.38e-118: 382: 16.67		H2A2C_HUMAN (7-134): 6.76e-52: 162: 55.04
+	Hs
		470016 HDAC1_HUMAN (47-552): 3.39e-136: 410: 11.94		H2AZ_HUMAN (10-134): 6.73e-41: 134: 67.72
+	Hs
		391684 HDAC1_HUMAN (47-552): 3.39e-136: 410: 11.94		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Sc
		866882 HDA1_YEAST (49-438): 3.75e-60: 216: 19.70		H2AZ_YEAST (1-134): 2.81e-53: 165: 100.00
+	Sc
		392177 HDA1_YEAST (49-438): 3.75e-60: 216: 19.70		H2A1_YEAST (23-133): 7.94e-52: 162: 62.50
+	Sc
		392527 HDA1_YEAST (49-438): 3.75e-60: 216: 19.70		H2A2_YEAST (23-133): 1.36e-51: 161: 62.50
+	Hs
		391948 HDAC6_HUMAN (68-433): 3.94e-75: 265: 19.78		H2A1B_HUMAN (8-126): 5.7e-31: 108: 60.83
+	Sp
		140568 PHD1_SCHPO (64-428): 7.52e-19: 91.9: 13.93		H2A2_SCHPO (10-131): 1.29e-51: 161: 58.54
+	Sp
		140612 PHD1_SCHPO (64-428): 7.52e-19: 91.9: 13.93		H2AZ_SCHPO (18-130): 1.98e-47: 151: 73.45