HitPredict

Interactor 1: M2OM (Q02978)
Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (alpha-oxoglutarate carrier) (Solute carrier family 25 member 11) (SLC25A11)
Gene: SLC25A11

Interactor 2: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	25852190, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 314 Hs			1 1374
+	Hs
		858278 TXTP_HUMAN (13-310): 1.49e-88: 269: 21.67		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		1168431 DIC_HUMAN (14-207): 1.66e-30: 118: 20.92		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		1168435 S2513_HUMAN (3-122): 5.08e-23: 101: 20.83		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		274564 S2512_HUMAN (3-122): 4.43e-20: 92.6: 19.17		LMTK1_HUMAN (1-1374): 0: 976: 100.00
+	Hs
		973955 M2OM_HUMAN (1-314): 1.66e-99: 297: 100.00		LMTK2_HUMAN (9-1366): 0: 690: 29.74
+	Hs
		412140 M2OM_HUMAN (1-314): 1.66e-99: 297: 100.00		FYN_HUMAN (104-408): 1.36e-104: 344: 30.07
+	Hs
		397352 ADT2_HUMAN (7-108): 1.65e-10: 62.9: 18.45		ACK1_HUMAN (54-854): 2.25e-146: 474: 21.51
+	Hs
		518252 ADT3_HUMAN (7-109): 3.4e-11: 64.8: 21.15		FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42
+	Hs
		507816 ADT3_HUMAN (7-109): 3.4e-11: 64.8: 21.15		FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00
+	Hs
		384680 M2OM_HUMAN (1-314): 1.66e-99: 297: 100.00		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		858264 TXTP_HUMAN (13-310): 1.49e-88: 269: 21.67		DDR2_HUMAN (108-395): 1.06e-36: 152: 33.86
+	Hs
		411572 ADT3_HUMAN (7-109): 3.4e-11: 64.8: 21.15		LCK_HUMAN (98-410): 1.51e-107: 352: 24.20
+	Hs
		384544 TXTP_HUMAN (13-310): 1.49e-88: 269: 21.67		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Rn
		544923 Q9EP88_RAT (78-307): 6.14e-44: 154: 19.74		INSR_RAT (111-395): 8.57e-39: 160: 35.25
+	Hs
		385661 DIC_HUMAN (14-207): 1.66e-30: 118: 20.92		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		1088154 S2513_HUMAN (3-122): 5.08e-23: 101: 20.83		DDR2_HUMAN (108-395): 1.06e-36: 152: 33.86
+	Hs
		385684 S2513_HUMAN (3-122): 5.08e-23: 101: 20.83		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		397233 ADT2_HUMAN (7-108): 1.65e-10: 62.9: 18.45		IGF1R_HUMAN (119-391): 2.65e-38: 159: 34.51
+	Hs
		384178 ADT3_HUMAN (7-109): 3.4e-11: 64.8: 21.15		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77
+	Hs
		384086 ADT2_HUMAN (7-108): 1.65e-10: 62.9: 18.45		NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77