Interactor 1: ENL (Q03111)
Protein ENL (YEATS domain-containing protein 1)
Gene: MLLT1

Interactor 2: SIR1 (Q96EB6)
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]
Gene: SIRT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 20431927
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001650 - fibrillar center
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0070577 - lysine-acetylated histone binding
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 559
Hs

1 747
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024