HitPredict

Interactor 1: MECOM (Q03112)
Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein homolog) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein) (Myelodysplasia syndrome-associated protein 1)
Gene: MECOM

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30462309
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1230 Hs			1 136
+	Hs
		935257 PRD16_HUMAN (1-1230): 0: 813: 44.40		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		1086322 PRD16_HUMAN (1-1230): 0: 813: 44.40		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1174663 PRD16_HUMAN (1-1230): 0: 813: 44.40		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		934680 MECOM_HUMAN (1-1230): 0: 666: 90.02		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		828201 MECOM_HUMAN (1-1230): 0: 666: 90.02		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Hs
		935116 ZN845_HUMAN (541-1230): 4.09e-149: 476: 12.62		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952548 ZN845_HUMAN (541-1230): 4.09e-149: 476: 12.62		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		935163 ZN184_HUMAN (966-1230): 1.06e-71: 257: 13.98		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952581 ZN184_HUMAN (966-1230): 1.06e-71: 257: 13.98		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		563247 ZNF12_HUMAN (903-1186): 1.9e-54: 205: 13.94		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		563250 ZNF12_HUMAN (903-1186): 1.9e-54: 205: 13.94		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		952558 ZN570_HUMAN (878-1111): 3e-45: 174: 22.76		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		935310 ZN226_HUMAN (2-144): 1.08e-21: 103: 9.72		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952664 ZN226_HUMAN (2-144): 1.08e-21: 103: 9.72		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		934803 ZKSC8_HUMAN (92-289): 6.95e-10: 65.1: 15.39		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		935001 ZN680_HUMAN (904-978): 3.11e-09: 63.2: 40.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27