HitPredict

Interactor 1: MECOM (Q03112)
Histone-lysine N-methyltransferase MECOM (EC 2.1.1.367) (Ecotropic virus integration site 1 protein homolog) (EVI-1) (MDS1 and EVI1 complex locus protein) (Myelodysplasia syndrome 1 protein) (Myelodysplasia syndrome-associated protein 1)
Gene: MECOM

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23858473
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1230 Hs			1 1102
+	Hs
		1273889 PRD16_HUMAN (1-1230): 0: 813: 44.40		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273793 ZN594_HUMAN (803-1229): 5.84e-112: 371: 15.45		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		970663 ZNF45_HUMAN (1068-1230): 3.07e-24: 111: 7.23		UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81
+	Hs
		599070 ZNF10_HUMAN (782-960): 1.81e-17: 89.7: 14.69		UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81
+	Hs
		1173892 ZN214_HUMAN (179-259): 5.95e-12: 72: 16.28		UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81
+	Hs
		1273719 ZN416_HUMAN (908-991): 1.33e-09: 64.3: 39.29		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08